Some properties of the pepsin natural inhibitor extracted from the marine gastropod Rapana thomassiana grosse

Authors

  • Natalia Roșoiu
  • M. Șerban
  • Maria Panait

Keywords:

antipeptic activity, Rapana thomasiana

Abstract

A natural inhibitor of pepsin, developing an intensive antipeptic activity, was separated and purified from the marine gastropod Rapana thomasiana Grosee; the value of the inhibition constant, ki, is only 0,009 mg/ml. This inhibitor is of peptidic nature, reacts almost instantaneously with the enzyme and causes an inhibition of the noncompetitive type as related to the hemoglobin used as a substrate. The inhibition developed is a function of the inhibitor concentration in the reaction medium and does not depend on the purity of the preparation used.

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Published

2026-07-29

How to Cite

Roșoiu, N., Șerban, M., & Panait, M. (2026). Some properties of the pepsin natural inhibitor extracted from the marine gastropod Rapana thomassiana grosse. Cercetări Marine - Recherches Marines, 15(1), 235–243. Retrieved from https://www.marine-research-journal.org/index.php/cmrm/article/view/613